Renal sulfate transport at the basolateral membrane is mediated by anion exchange.
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چکیده
منابع مشابه
Renal sulfate transport at the basolateral membrane is mediated by anion exchange.
The transport of sulfate was studied in basolateral membrane (BLM) vesicles isolated from rat kidney cortex by centrifugation on a Percoll self-generating gradient. In contrast to sulfate transport at the luminal membrane, sulfate uptake by BLM vesicles was not sodium dependent. However, imposition of an inside greater than outside bicarbonate gradient stimulated BLM sulfate uptake nearly 10-fo...
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Purified basolateral membrane vesicles were prepared from the intestinal epithelium of the tilapia Oreochromis mossambicus, a herbivorous teleost. Characteristics of volatile fatty acid (VFA) transport were investigated using [H]acetate as a representative anion. No significant change in [H]acetate influx was observed in the presence of a cation gradient (K or Na) compared to the influx observe...
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The transport of bile acid was studied in basolateral membrane vesicles isolated from rat small intestine. Taurocholate transport into an osmotically reactive intravesicular space was Na+ independent. The uptake of taurocholate in jejunal and ileal vesicles preloaded with sulfate was stimulated with respect to uptake in unpreloaded vesicles. Glycocholate inhibited the transstimulation of tauroc...
متن کاملA dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines.
The sat-1 transporter mediates sulfate/bicarbonate/oxalate anion exchange in vivo at the basolateral membrane of the kidney proximal tubule. In the present study, we show two renal cell lines [Madin-Darby canine kidney (MDCK) and porcine proximal tubular kidney (LLC-PK1) cells] that similarly target sat-1 exclusively to the basolateral membrane. To identify possible sorting determinants, we gen...
متن کاملCalcium Transport in Canine Renal Basolateral Membrane Vesicles
Introduction The effects of parathyroid hormone were studied on Ca" fluxes in canine renal proximal tubular basolateral membrane vesicles (BLMV). Efflux of Ca2+ from preloaded BLMV was found to be stimulated by an external Na' gradient, and this was inhibited by the Na' ionophore, monensin, and enhanced by intravesicular negative electrical potentials, which indicated electrogenic Na+/Ca2" exch...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1983
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.80.9.2603